The North American preventive vaccines market is a dynamic and rapidly evolving sector within the broader pharmaceutical industry. It encompasses a wide range of vaccines aimed at preventing infectious diseases across various age groups, from infants and children to adolescents and adults. This market has witnessed significant growth in recent years, driven by several key factors. Firstly, the increasing prevalence of infectious diseases, including both established and emerging ones, has heightened the demand for effective preventive measures like vaccines. Secondly, growing awareness among the population about the importance of vaccination and preventive healthcare has contributed to increased vaccine uptake. Thirdly, advancements in vaccine technology, such as the development of novel vaccine platforms like mRNA vaccines, have expanded the range of preventable diseases and improved vaccine efficacy and safety profiles. Fourthly, substantial investments in research and development by both public and private sectors have fueled innovation and the introduction of new vaccines. Additionally, supportive government initiatives, including immunization programs and public health campaigns, have played a crucial role in driving vaccine adoption rates. The North American preventive vaccines market is characterized by the presence of major global pharmaceutical companies, as well as smaller specialized players, leading to a competitive landscape. These companies are engaged in continuous research and development efforts to introduce new and improved vaccines, catering to the evolving healthcare needs of the population. The market is segmented based on various factors, including vaccine type, disease indication, age group, and distribution channel. The vaccine market is further segmented into viral and bacterial vaccines, with viral vaccines dominating the market due to the high prevalence of viral infections. The market is also segmented by age group, with pediatric vaccines accounting for a significant share due to the emphasis on childhood immunization. The distribution channels for vaccines include hospitals, clinics, government agencies, and pharmacies, with hospitals and clinics being the primary points of vaccine administration. The North American preventive vaccines market is expected to continue its growth trajectory in the coming years, driven by the ongoing factors mentioned above, as well as the increasing focus on preventive healthcare and the development of new and innovative vaccines.

North America preventive vaccines market is expected to grow by 10.42% annually in the forecast period and reach $34.02 billion by 2030 owing to increasing healthcare expenditure, new development of the vaccines, and rising need for preventive vaccines especially new COVID-19 vaccines. The North American preventive vaccines market is a robust and expanding sector driven by a confluence of factors. The increasing incidence of infectious diseases, both established and emerging, fuels the demand for preventive measures like vaccines. Simultaneously, heightened public awareness regarding the significance of vaccination and preventive healthcare contributes to increased vaccine uptake. Technological breakthroughs, exemplified by the development of mRNA vaccines and other innovative platforms, are broadening the spectrum of preventable diseases and enhancing vaccine efficacy and safety. Substantial investments in research and development, both from public and private entities, propel innovation and the introduction of novel vaccines. Supportive government initiatives, such as immunization programs and public health campaigns, play a pivotal role in promoting vaccine adoption rates. The market is characterized by a competitive landscape featuring major global pharmaceutical companies and smaller specialized players, all engaged in continuous research and development to introduce new and improved vaccines. This dynamic market is segmented based on vaccine type, disease indication, age group, and distribution channel, with viral vaccines currently dominating due to the high prevalence of viral infections. Pediatric vaccines hold a significant market share due to the emphasis on childhood immunization, while distribution channels primarily include hospitals and clinics, the primary points of vaccine administration. The market is further influenced by trade programs, including government procurement programs, public-private partnerships, international collaborations, trade agreements, and vaccine assistance programs, all contributing to ensuring vaccine accessibility and affordability. In essence, the North American preventive vaccines market is poised for continued growth, fueled by ongoing factors, the increasing focus on preventive healthcare, and the development of new and innovative vaccines.

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The North American preventive vaccines market is segmented by vaccine type, encompassing a diverse range of vaccines designed to protect against various infectious diseases. This segmentation allows for a granular understanding of market dynamics, as each vaccine type caters to specific disease targets and often utilizes distinct technological approaches. Broadly, the market can be categorized into several key vaccine types. Viral vaccines constitute a significant portion of the market, addressing a wide range of viral infections. These include vaccines for diseases like influenza, measles, mumps, rubella (MMR), varicella (chickenpox), hepatitis A and B, human papillomavirus (HPV), polio, and more recently, COVID-19 vaccines. Viral vaccines employ various mechanisms, such as live attenuated viruses, inactivated viruses, viral subunits, or viral vectors, to stimulate an immune response. The high prevalence of viral infections and the success of vaccination programs against many viral diseases contribute to the dominance of this segment. Bacterial vaccines target infections caused by bacteria. This category includes vaccines against diseases like diphtheria, tetanus, pertussis (whooping cough), pneumococcal disease, meningococcal disease, Haemophilus influenzae type b (Hib), and certain types of bacterial meningitis. Bacterial vaccines often utilize inactivated bacterial toxins, bacterial cell components, or conjugated polysaccharides to induce immunity. The increasing threat of antibiotic resistance has further emphasized the importance of bacterial vaccines in preventing and controlling bacterial infections. Conjugate vaccines represent a specialized type of vaccine that links a polysaccharide antigen from a bacterium to a carrier protein. This conjugation enhances the immune response, particularly in young children, making these vaccines more effective against encapsulated bacteria like those causing Hib and some types of pneumococcal and meningococcal disease. Toxoid vaccines are designed to protect against diseases caused by bacterial toxins. These vaccines contain inactivated toxins, or toxoids, that stimulate the production of antitoxins, neutralizing the harmful effects of the toxins. Tetanus and diphtheria vaccines are examples of toxoid vaccines. Subunit vaccines contain only specific components or subunits of a pathogen, such as proteins or polysaccharides, rather than the whole organism.


The North American preventive vaccines market is segmented by disease, reflecting the diverse range of infectious diseases that vaccines are designed to prevent. This segmentation allows for a targeted approach to immunization strategies, addressing specific public health needs and prioritizing the prevention of prevalent and potentially serious infections. The disease segment encompasses a broad spectrum of illnesses, categorized by the causative agent (viral, bacterial, etc.) and the specific health condition they cause. Viral diseases represent a substantial portion of the market, with vaccines available for a multitude of viral infections. These include influenza, a highly contagious respiratory illness with various strains; measles, mumps, and rubella (MMR), childhood diseases that can lead to serious complications; varicella (chickenpox), a common childhood infection; hepatitis A and B, liver diseases; human papillomavirus (HPV), a sexually transmitted virus linked to several cancers; polio, a debilitating disease affecting the nervous system; and, most recently, COVID-19, a pandemic respiratory illness. The development and widespread use of vaccines against these viral diseases have significantly reduced their incidence and impact on public health. Bacterial diseases are another significant target for preventive vaccines. This segment includes vaccines against diphtheria, tetanus, and pertussis (whooping cough), often administered as a combined DTaP vaccine; pneumococcal disease, caused by Streptococcus pneumoniae bacteria, leading to pneumonia, meningitis, and other infections; meningococcal disease, caused by Neisseria meningitidis bacteria, resulting in meningitis and septicemia; Haemophilus influenzae type b (Hib), a bacterium that can cause meningitis and other serious infections, particularly in young children; and certain types of bacterial meningitis. Vaccines against these bacterial diseases have been instrumental in reducing childhood morbidity and mortality.


The North American preventive vaccines market is experiencing significant growth, driven by a confluence of factors including an aging population, rising prevalence of infectious diseases, increasing awareness about preventive healthcare, and advancements in vaccine technology. The market is highly competitive, with major players like Pfizer, Merck, GSK, and Sanofi investing heavily in research and development to introduce innovative vaccines for various diseases. One of the key trends in the market is the growing adoption of combination vaccines, which offer protection against multiple diseases in a single shot, thereby improving patient compliance and reducing healthcare costs. Additionally, there is a rising demand for vaccines targeting chronic diseases such as cancer and autoimmune disorders, which is expected to fuel market growth in the coming years. Furthermore, the increasing focus on immunization programs by governments and public health organizations is also contributing to the market's expansion. For instance, the US government's "Vaccines for Children" program provides vaccines at no cost to eligible children, which has significantly increased vaccination rates in the country. The North American market is also witnessing a surge in the development and adoption of novel vaccine technologies such as mRNA vaccines, which have shown promising results in recent clinical trials. These vaccines offer several advantages over traditional vaccines, including faster development times, higher efficacy, and improved safety profiles. Moreover, the market is benefiting from the growing investments in research and development by both public and private organizations, which are aimed at developing new and improved vaccines for a wide range of diseases. Despite the positive growth outlook, the North American preventive vaccines market faces certain challenges.

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Manmayi Raval

Manmayi Raval

Research Consultant





The North American preventive vaccines market caters to a diverse patient population, segmented primarily by age and health status. Infants and children form a significant segment, driven by mandatory vaccination schedules for diseases like measles, mumps, rubella, polio, and diphtheria, tetanus, and pertussis (DTaP). This segment benefits from high vaccination rates due to strong parental awareness and government-funded immunization programs. Adolescents represent another key segment, with vaccinations recommended for diseases like human papillomavirus (HPV) and meningococcal meningitis. Adults, particularly those aged 65 and above, constitute a growing segment due to increased susceptibility to infectious diseases like influenza, pneumococcal pneumonia, and shingles. This segment is also targeted for booster shots of childhood vaccines to maintain immunity. Additionally, individuals with chronic conditions like diabetes, heart disease, and lung disease form a vulnerable segment, requiring specific vaccinations to prevent complications from infections. Furthermore, the market caters to specific at-risk groups, such as healthcare workers, travelers, and immunocompromised individuals, with tailored vaccination recommendations. The increasing prevalence of chronic diseases and the growing geriatric population are driving the demand for adult vaccinations, making it a crucial segment for market growth. Moreover, rising awareness about preventive healthcare and the availability of newer vaccines are encouraging more adults to seek vaccination. The patient segment is also influenced by factors like socioeconomic status, education level, and access to healthcare, which impact vaccination uptake. While cost can be a barrier for some individuals, government initiatives and insurance coverage play a crucial role in improving access to vaccines. Vaccine hesitancy and misinformation pose a challenge, particularly among certain demographics, highlighting the need for effective communication and education campaigns to promote vaccine confidence.


The North American preventive vaccines market is primarily concentrated in two major countries: the United States and Canada. The United States holds the largest share of the market, driven by its advanced healthcare infrastructure, high healthcare expenditure, and a large population base. The US market is characterized by a strong emphasis on preventive care, with high vaccination rates for both children and adults. The presence of major vaccine manufacturers, robust research and development activities, and favorable regulatory frameworks further contribute to the growth of the US market. Canada, while smaller in size, also represents a significant market for preventive vaccines, with a well-established healthcare system and increasing awareness about preventive healthcare. The Canadian government's focus on immunization programs and public health initiatives supports the growth of the vaccine market in the country. Both the US and Canada have well-defined immunization schedules for different age groups, which drives the demand for various vaccines. The market is also influenced by factors such as disease prevalence, public health campaigns, and vaccine coverage rates. In addition to these two major countries, the North American market also includes smaller countries like Mexico, which presents growth opportunities due to its large population and increasing healthcare awareness. However, factors such as economic conditions, access to healthcare, and cultural beliefs can influence vaccine uptake in these countries. The North American preventive vaccines market is dominated by the US, followed by Canada, with both countries exhibiting strong growth potential due to favorable healthcare infrastructure, increasing awareness, and government support for immunization programs.

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Manmayi Raval

Table of Contents

  • 1 Introduction 7
  • 1.1 Industry Definition and Research Scope 7
  • 1.1.1 Industry Definition 7
  • 1.1.2 Research Scope 8
  • 1.2 Research Methodology 11
  • 1.2.1 Overview of Market Research Methodology 11
  • 1.2.2 Market Assumption 12
  • 1.2.3 Secondary Data 12
  • 1.2.4 Primary Data 12
  • 1.2.5 Data Filtration and Model Design 13
  • 1.2.6 Market Size/Share Estimation 14
  • 1.2.7 Research Limitations 15
  • 1.3 Executive Summary 16
  • 2 Market Overview and Dynamics 19
  • 2.1 Market Size and Forecast 19
  • 2.1.1 Impact of COVID-19 on World Economy 21
  • 2.1.2 Impact of COVID-19 on the Market 23
  • 2.2 Major Growth Drivers 25
  • 2.3 Market Restraints and Challenges 28
  • 2.4 Emerging Opportunities and Market Trends 31
  • 2.5 Porter’s Fiver Forces Analysis 35
  • 3 Segmentation of North America Market by Vaccine Type 39
  • 3.1 Market Overview by Vaccine Type 39
  • 3.2 Live/Attenuated Vaccines 41
  • 3.3 Inactivated Vaccines 42
  • 3.4 Subunit Vaccines 43
  • 3.5 Toxoid Vaccines 44
  • 3.6 Conjugate Vaccines 45
  • 3.7 Recombinant Vector Vaccines 46
  • 3.8 Other Vaccines 47
  • 4 Segmentation of North America Market by Disease 48
  • 4.1 Market Overview by Disease 48
  • 4.2 Vaccines for Pneumococcal Disease 50
  • 4.3 Vaccines for Poliovirus 51
  • 4.4 Vaccines for Hepatitis 52
  • 4.5 Vaccines for Influenza 53
  • 4.6 Vaccines for Measles, Mumps, and Rubella (MMR) 54
  • 4.7 Vaccines for Varicella 55
  • 4.8 Vaccines for Human Papilloma Virus 56
  • 4.9 Vaccines for COVID-19 57
  • 4.10 Vaccines for Other Diseases 60
  • 5 Segmentation of North America Market by Administration 61
  • 5.1 Market Overview by Administration 61
  • 5.2 Intramuscular Route 63
  • 5.3 Subcutaneous Route 64
  • 5.4 Oral Route 65
  • 5.5 Intravenous Injection 66
  • 5.6 Other Administration Routes 67
  • 6 Segmentation of North America Market by Patient 68
  • 6.1 Market Overview by Patient 68
  • 6.2 Pediatric Vaccines 70
  • 6.3 Adult Vaccines 72
  • 7 North America Market 2020-2026 by Country 74
  • 7.1 Overview of North America Market 74
  • 7.2 U.S. 77
  • 7.3 Canada 82
  • 7.4 Mexico 85
  • 8 Competitive Landscape 88
  • 8.1 Overview of Key Vendors 88
  • 8.2 New Product Launch, Partnership, Investment, and M&A 91
  • 8.3 Company Profiles 92
  • AstraZeneca plc 92
  • Bavarian Nordic A/S 95
  • China National Biotec Group Company Ltd. 98
  • CSL Ltd. 100
  • Daiichi Sankyo Co. Ltd 102
  • Emergent BioSolutions Inc. 104
  • GlaxoSmithKline plc 106
  • Johnson & Johnson 110
  • Merck & Co. 112
  • Moderna Inc. 114
  • Novavax, Inc. 115
  • Pfizer Inc. 117
  • Sanofi SA 121
  • Takeda Pharmaceutical Co. Ltd. 123
  • 9 Investing in North America Market: Risk Assessment and Management 125
  • 9.1 Risk Evaluation of North America Market 125
  • 9.2 Critical Success Factors (CSFs) 128
  • Related Reports and Products 131

Table 1. Snapshot of North America Preventive Vaccines Market in Balanced Perspective, 2020-2026 17
Table 2. Growth Rate of World GDP, 2020-2022 22
Table 3. Main Product Trends and Market Opportunities in North America Preventive Vaccines Market 31
Table 4. North America Preventive Vaccines Market by Vaccine Type, 2016-2026, $ mn 39
Table 5. North America Preventive Vaccines Market by Disease, 2016-2026, $ mn 48
Table 6. COVID-19 Vaccines Authorized for Emergency Use or Approved for Full Use, as of April 2021 58
Table 7. North America Preventive Vaccines Market by Administration, 2016-2026, $ mn 61
Table 8. North America Preventive Vaccines Market by Patient, 2016-2026, $ mn 68
Table 9. North America Preventive Vaccines Market: Pediatric Vaccines by Disease, 2016-2026, $ mn 71
Table 10. North America Preventive Vaccines Market: Adult Vaccines by Disease, 2016-2026, $ mn 73
Table 11. North America Preventive Vaccines Market by Country, 2016-2026, $ mn 75
Table 12. U.S. Preventive Vaccines Market by Vaccine Type, 2016-2026, $ mn 79
Table 13. U.S. Preventive Vaccines Market by Disease, 2016-2026, $ mn 79
Table 14. U.S. Preventive Vaccines Market by Administration, 2016-2026, $ mn 80
Table 15. Canada Preventive Vaccines Market by Vaccine Type, 2016-2026, $ mn 83
Table 16. Canada Preventive Vaccines Market by Disease, 2016-2026, $ mn 83
Table 17. Canada Preventive Vaccines Market by Administration, 2016-2026, $ mn 84
Table 18. Mexico Preventive Vaccines Market by Vaccine Type, 2016-2026, $ mn 86
Table 19. Mexico Preventive Vaccines Market by Disease, 2016-2026, $ mn 86
Table 20. Mexico Preventive Vaccines Market by Administration, 2016-2026, $ mn 87
Table 21. AstraZeneca plc: Company Snapshot 92
Table 22. AstraZeneca plc: Revenue, 2018-2020, $ bn 93
Table 23. Bavarian Nordic A/S: Company Snapshot 95
Table 24. Bavarian Nordic A/S: Marketed Products and Pipeline, as of July 2020 96
Table 25. China National Biotec Group Company Ltd.: Company Snapshot 98
Table 26. CSL Ltd.: Company Snapshot 100
Table 27. Daiichi Sankyo Co. Ltd.: Company Snapshot 102
Table 28. Emergent BioSolutions Inc.: Company Snapshot 104
Table 29. GlaxoSmithKline: Company Snapshot 106
Table 30. GlaxoSmithKline: Business Segmentation 107
Table 31. GlaxoSmithKline: Product Portfolio 108
Table 32. GlaxoSmithKline: Revenue, 2018-2020, $ bn 109
Table 33. GlaxoSmithKline: Recent Developments 109
Table 34. Johnson & Johnson: Company Snapshot 110
Table 35. Johnson & Johnson: Business Segments 111
Table 36. Merck & Co., Inc.: Company Snapshot 112
Table 37. Merck & Co., Inc.: Business Segmentation 112
Table 38. Merck & Co., Inc.: Revenue, 2018-2020, $ bn 113
Table 39. Moderna Inc.: Company Snapshot 114
Table 40. Novavax, Inc.: Company Snapshot 115
Table 41. Pfizer Inc.: Company Snapshot 117
Table 42. Pfizer Inc.: Business Segmentation 118
Table 43. Pfizer Inc.: Product Portfolio 119
Table 44. Pfizer Inc.: Revenue, 2018-2020, $ bn 120
Table 45. Pfizer Inc.: Recent Developments 120
Table 46. Sanofi: Company Snapshot 121
Table 47. Sanofi: Business Segmentation 121
Table 48. Sanofi: Revenue, 2018-2020, $ bn 122
Table 49. Takeda Pharmaceutical Co. Ltd.: Company Snapshot 123
Table 50. Risk Evaluation for Investing in North America Market, 2020-2026 126
Table 51. Critical Success Factors and Key Takeaways 129

Figure 1. Research Method Flow Chart 11
Figure 2. Bottom-up Approach and Top-down Approach for Market Estimation 14
Figure 3. North America Market Forecast in Optimistic, Conservative and Balanced Perspectives, 2020-2026 16
Figure 4. North America Preventive Vaccines Market, 2016-2026, $ mn 19
Figure 5. Development Stages of Preventive Vaccines 20
Figure 6. Impact of COVID-19 on Business 23
Figure 7. Primary Drivers and Impact Factors of North America Preventive Vaccines Market 25
Figure 8. Primary Restraints and Impact Factors of North America Preventive Vaccines Market 28
Figure 9. Investment Opportunity Analysis 32
Figure 10. Porter’s Fiver Forces Analysis of North America Preventive Vaccines Market 35
Figure 11. Breakdown of North America Preventive Vaccines Market by Vaccine Type, 2020-2026, % of Revenue 40
Figure 12. Contribution to North America 2021-2026 Cumulative Revenue by Vaccine Type, Value ($ mn) and Share (%) 40
Figure 13. North America Preventive Vaccines Market: Live/Attenuated Vaccines, 2016-2026, $ mn 41
Figure 14. North America Preventive Vaccines Market: Inactivated Vaccines, 2016-2026, $ mn 42
Figure 15. North America Preventive Vaccines Market: Subunit Vaccines, 2016-2026, $ mn 43
Figure 16. North America Preventive Vaccines Market: Toxoid Vaccines, 2016-2026, $ mn 44
Figure 17. North America Preventive Vaccines Market: Conjugate Vaccines, 2016-2026, $ mn 45
Figure 18. North America Preventive Vaccines Market: Recombinant Vector Vaccines, 2016-2026, $ mn 46
Figure 19. North America Preventive Vaccines Market: Other Vaccines, 2016-2026, $ mn 47
Figure 20. Breakdown of North America Preventive Vaccines Market by Disease, 2020-2026, % of Revenue 49
Figure 21. Contribution to North America 2021-2026 Cumulative Revenue by Disease, Value ($ mn) and Share (%) 49
Figure 22. North America Preventive Vaccines Market: Vaccines for Pneumococcal Disease, 2016-2026, $ mn 50
Figure 23. North America Preventive Vaccines Market: Vaccines for Poliovirus, 2016-2026, $ mn 51
Figure 24. North America Preventive Vaccines Market: Vaccines for Hepatitis, 2016-2026, $ mn 52
Figure 25. North America Preventive Vaccines Market: Vaccines for Influenza, 2016-2026, $ mn 53
Figure 26. North America Preventive Vaccines Market: Vaccines for Measles, Mumps, and Rubella (MMR), 2016-2026, $ mn 54
Figure 27. North America Preventive Vaccines Market: Vaccines for Varicella, 2016-2026, $ mn 55
Figure 28. North America Preventive Vaccines Market: Vaccines for Human Papilloma Virus, 2016-2026, $ mn 56
Figure 29. North America Preventive Vaccines Market: Vaccines for COVID-19, 2016-2026, $ mn 57
Figure 30. North America Preventive Vaccines Market: Vaccines for Other Diseases, 2016-2026, $ mn 60
Figure 31. Breakdown of North America Preventive Vaccines Market by Administration, 2020-2026, % of Revenue 62
Figure 32. Contribution to North America 2021-2026 Cumulative Revenue by Administration, Value ($ mn) and Share (%) 62
Figure 33. North America Preventive Vaccines Market: Intramuscular Route, 2016-2026, $ mn 63
Figure 34. North America Preventive Vaccines Market: Subcutaneous Route, 2016-2026, $ mn 64
Figure 35. North America Preventive Vaccines Market: Oral Route, 2016-2026, $ mn 65
Figure 36. North America Preventive Vaccines Market: Intravenous Injection, 2016-2026, $ mn 66
Figure 37. North America Preventive Vaccines Market: Other Administration Routes, 2016-2026, $ mn 67
Figure 38. Breakdown of North America Preventive Vaccines Market by Patient, 2020-2026, % of Revenue 68
Figure 39. Contribution to North America 2021-2026 Cumulative Revenue by Patient, Value ($ mn) and Share (%) 69
Figure 40. North America Preventive Vaccines Market: Pediatric Vaccines, 2016-2026, $ mn 70
Figure 41. North America Preventive Vaccines Market: Adult Vaccines, 2016-2026, $ mn 72
Figure 42. Breakdown of North America Preventive Vaccines Market by Country, 2020 and 2026, % of Revenue 75
Figure 43. Contribution to North America 2021-2026 Cumulative Revenue by Country, Value ($ mn) and Share (%) 76
Figure 44. U.S. Preventive Vaccines Market, 2016-2026, $ mn 78
Figure 45. Canada Preventive Vaccines Market, 2016-2026, $ mn 82
Figure 46. Preventive Vaccines Market in Mexico, 2016-2026, $ mn 85
Figure 47. Growth Stage of North America Preventive Vaccines Industry over the Forecast Period 88
Figure 48. Top Products of AstraZeneca Based on Revenue from 2016 to 2019 (in million U.S. dollars) 93
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North America Preventive Vaccines Market Outlook, 2030

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